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The Food and Drug Administration (FDA) is responsible for assessing the safety of medical devices in the United States. The FDA's role involves evaluating new medical devices before they can be marketed, ensuring they meet established safety and effectiveness standards. This agency conducts rigorous reviews of clinical data and manufacturing processes to protect public health.

In addition to pre-market evaluations, the FDA also monitors medical devices once they are on the market. This post-market surveillance allows the agency to respond to any safety concerns that may arise, thereby ensuring ongoing oversight of device safety throughout its lifecycle.

The other organizations mentioned in the choices have different roles: the Centers for Disease Control and Prevention (CDC) primarily focuses on public health and disease prevention; the National Institutes of Health (NIH) oversees medical research and funding rather than device safety; and the Occupational Safety and Health Administration (OSHA) is concerned with workplace safety and regulations, rather than the safety of medical devices themselves.